Market Research Analyst: May 2017

Monday 29 May 2017

Global Streptococci Testing Market By Analysis of Major Industry Segments 2016 - 2024

Streptococci Testing Market: Overview

Streptococcal infections are caused by a microorganism called Streptococcus which is a non-motile, microaerophilic, grampositive spherical bacterium. Several disease causing strains of the bacteria include streptococci (groups A, B, C, D, and G). Each group causes specific types of infections and symptoms. Group A strain of the bacteria are the most virulent species for humans and cause wound and skin infections, strep throat, scarlet fever, tonsillitis, blood infections (septicemia), pneumonia, Sydenham's chorea., rheumatic fever and glomerulonephritis.

Streptococci are known to originate from several natural sources, including humans and diverse animals. These bacteria often colonize on the mucosal surfaces of the mouth, nasal passages, intestinal tract, and pharynx. Moreover, the bacteria may also cause contamination of drinking water due to feces. Food products which are at high risk of contamination include milk and dairy products, steamed lobster, eggs, potato salad, ground ham, rice pudding custard, and shrimp salad. Some streptococci are commercially important for the production of cheese and yogurt, though are known to be potent pathogen.

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The bacteria species which do not cause any infection and are used in food industry include S. lactis, S. diacelillactis S. cremoris, and S. thermophilus, the latter being the most well-known. The factors affecting the incidences of sore throats (pharyngitis) include seasonal variation, patient’s age, and geography. Pharyngitis most of the times is bacterial, though can be viral. Children ranging from 5 to 15 years of age are most susceptible to the infection by group A strep during the winter or early spring season. Symptoms of this infection include stomach aches, headaches, vomiting, nausea, and listlessness.

Streptococci Testing Market: Key Segments

The global streptococci testing market can be segmented based in tests type, end users and geography. Antibody tests include the antistreptolysin O titer (ASO), anti-DNase-B (ADB) test and Streptozyme. ASO test helps in determining a kidney disease glomerulonephritis, scarlet fever or rheumatic fever. ADB test is performed to determine a previous infection of a group A beta-hemolytic Streptococcus. Streptozyme is a screening test used to detect antibodies to several streptococcal antigens. Diagnostic tests include throat culture and rapid antigen test. Diagnostic tests are used to confirm the infection where in the sample from the infected area is used as culture, a means of growing bacteria artificially in the laboratory.

The cause of a sore throat is usually diagnosed on the basis of a physical exam and lab tests. A throat culture also known as strep test helps in detection of the presence of group A strain of streptococcal bacteria by using a throat swab. This strain is the most common cause of strep throat infection. Various other infections caused by these bacteria include pneumonia, meningitis and tonsillitis. Rapid antigen test can detect strep bacteria in minutes by looking for substances (antigens) in the throat. The rapid strep test detects the presence of a carbohydrate antigen which is unique to group A Streptococcus.

The downside to the rapid test is that it cannot detect the presence of Group C and G which can also cause streptococcal pharyngitis. On positive rapid strep test, the treatment is started with appropriate antibiotics to prevent long-term damage and recurrence. End users segment include hospitals, private labs, physicians offices and public health labs. Geographically, the global streptococci testing market is segmented into four major regions namely, North America, Europe, Asia-Pacific and Rest of the World.

Streptococci Testing Market: Key Players

The key players contributing to Streptococci market include Abbott Diagnostics, Beckman Coulter, bioMerieux, DiaSorin, Hologic, Qiagen, Roche Diagnostics, Novartis Diagnostics, Ortho Clinical Diagnostics, Sigma Aldrich, and Thermo Fischer Scientific.

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Transparency Market Research (TMR) is a market intelligence company, providing global business information reports and services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insight for thousands of decision makers. We have an experienced team of Analysts, Researchers, and Consultants, who us e proprietary data sources and various tools and techniques to gather, and analyze information. Our business offerings represent the latest and the most reliable information indispensable for businesses to sustain a competitive edge.

Global Medical Pendant Systems Market Analysis, Trends and Forecast by 2016 - 2024

The growing need for a safe and low-risk work space for the medical workforce is driving the global medical pendant systems market. Medical pendant systems help provide correct positioning of terminal units, medical equipment, medical gas, and specialty and electrical services, thus fulfilling the requirements of a hospital. Moreover, since electrical and gas services are facilitated from the ceiling, cable clutter is eliminated, making the place safer and cleaner for activities and movement of medical professionals.

The global medical pendant systems market is segmented on the basis of type, application, and geography. On the basis of product the market is segmented into fixed, fixed retractable, double multi-arm, and single arm movable. By application, the global medical pendant systems market is segmented into surgery, anesthesia, endoscopy, and ICU.

The report offers a detailed overview of the market segments and sub-segments. The trends and opportunities in the market are discussed at length. A detailed analysis of factors driving and restricting the market has been included. The report presents an evaluation of the market by making use of historical data, current market status, and qualitative insights. The macro and microeconomic indicators have also been analyzed in the study.

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Overview of the Medical Pendant Systems Market

The global medical pendant systems market is driven by the growing need for these systems in intensive care units and operating theaters. The adoption of medical pendant systems has been fueled by the effective results achieved in the areas of endoscopy and surgery. A growing demand for medical support systems with advanced features is another factor driving the market. Moreover, innovation and technological advancements enabling medical pendant systems to move as needed by the press of a button are encouraging the adoption of these systems. However, the market is restricted by the high cost of medical pendant systems, causing many hospitals to hesitate in adopting these systems. Hospitals unable to afford these systems contemplate using alternatives, which can be a threat to the growth of the market.

The rising demand for flexible, more space saving, and light-weight systems and systems with multiple features is compelling manufacturers to design and develop newer systems with advanced features. This is leading to many product innovations and will thus boost the demand for medical pendant systems. Another trend in the market is the development of medical pendant systems with higher number of electrical points and gas services. The high usage of electronic devices by hospitals is driving this trend. Such innovations in products are expected to open new doors of opportunities in the market.

The global medical pendant systems market is segmented on the basis of geography into Europe, Asia Pacific, North America, and the Rest of the World. Of these, North America led the market in 2015. The market in Asia Pacific is expected to grow considerably owing to higher investments in the healthcare sector. By type, the demand for fixed retractable medical pendants is expected to be high, as per TMR analysts.

Companies Mentioned in the Report

The report profiles major players operating in the global medical pendant systems market. The business and financial overviews of each of the companies have been included. Factors driving and limiting the growth of the companies are also included. The report includes strategies adopted by key players, their recent developments, and product picture and specifications. This enables readers and enterprises to make informed decisions regarding investments in the global medical pendant systems market. Following are the companies studied in the report: ELEKTRA HELLAS, Uttam,Starkstrom, Hipac, Unicorn Medicals, Ondal, Brandon Medical, Beacon Medaes, Medilon, and Medimax.

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Global Restless Legs Syndrome Treatment Market By Analysis of Major Industry Segments 2016 - 2024

Global Restless Legs Syndrome Treatment Market: Overview

Restless legs syndrome, also called Willis-Ekbom disease, is a neurological disorder. It triggers an urge in patients to move their legs. Because the syndrome usually occurs during sleep, it is also considered a type of sleep disorder. People suffering from restless legs syndrome often feel an overwhelming desire to rigorously move their legs, the intensity and frequency of which leads to unpleasant pain in their limbs. This also disturbs their sleep patterns, affecting their health adversely. The condition usually aggravates at night.

Higher prevalence of restless legs syndrome is noted in women than in men. RLS can affect people of all ages but is mostly observed in middle-aged and elderly people. The most common symptoms of RLS include uncomfortable itching and pain in the legs that may cause a disruption in the sleep pattern and ultimately affect a patient’s quality of life. Despite its increasing prevalence, the precise cause of RLS is not yet known. Nevertheless, with extensive investigations being conducted in the field, the RLS market is expected to gain momentum in the near future. As of now, experts attribute the increasing incidence of the disease to genetic factors and instabilities in the dopaminergic balance.

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While researchers are yet to discover a specific cure for the disorder, drugs presently available in the market ensure symptomatic treatment. They help in relieving the uneasiness commonly experienced in the disorder. The report studies the prospects for the global restless legs syndrome treatment market in the forthcoming years. The impact of research and development activities on the market’s future outlook is examined in the report in detail. It also presents insights into the various social and economic factors that will influence the market’s growth trajectory between 2016 and 2024.

Global Restless Legs Syndrome Treatment Market: Opportunities and Market Segmentation

Restless legs syndrome causes uneasiness in patients and is also associated with other health issues such as dizziness, headaches, drowsiness, flatulence, dry mouth, and nausea. Patients suffering from restless legs syndrome may also suffer from psychiatric disorders such as depression and a decreased libido. Apart from these, labyrinthitis and other ear disorders, fatigue, irritability, peripheral edema, and nutritional and metabolism disorders indicated by weight gain or increased appetite are also related to the syndrome.

The treatment of restless legs syndrome is still a relatively untapped space. The market is projected to exhibit growth at an increased rate with the development of new drugs, which promise higher efficiency and minimum side effects.

Based on product type, the global restless legs syndrome treatment market can be segmented into Neupro/Leganto, Mirapex/Sifrol/Mirapexin, HORIZANT/Regnite, and Requip. Restless legs syndrome treatment can be segmented into pharmacological and nonpharmacological.

Global Restless Legs Syndrome Treatment Market: Competitive Insights

In order to study the competitive landscape prevailing in the market, the report profiles companies such as GlaxoSmithKline plc., Kyowa Hakko Kirin Co., Boehringer Ingelheim GmbH, Jazz Pharmaceuticals, Inc., and Manhattan Pharmaceuticals. The strengths and weaknesses of the companies are weighed out in the report using SWOT analysis. The analysis also helps the report gauge the threats and opportunities that these companies could face in the near future.

The report offers a complete databank about the global restless legs syndrome treatment market by providing in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information regarding every facet of the market.

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Global Lithotripsy Device Market Share by Industry Research 2016 - 2024

Lithotripsy is the treatment used to cure stones or other calculus in kidney or other organ of body such as gall bladder or liver. Stones occur due to deposition of minerals and other substances in crystalline form. Stones appear in different forms such as tiny small stones, sharp-edged, large size stones. Stones are usually removed from the body through urination. Large size stones are not able to pass through routine urination. Lithotripsy is a procedure where sound waves are used to break large stones into tiny particles which can be easily excreted through urination. The shock waves used in lithotripsy are high energy shock waves.

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Lithotripsy is an outpatient treatment. High energy shock waves are generated which are allowed to pass through the body to the site where stone is present. These waves break the large stone into tiny small particles, which are easily removed from the body through normal urination process. It is a non-invasive procedure to get rid of stones with the help of acoustic pulse. It is used to treat stones of kidney, gall bladder, and liver, and have been reported to be used for treatment of salivary stones and pancreatic stones. Lithotripsy is a non-invasive procedure, which is preferred to surgery. A patient does not need to get hospitalized and is discharged on the same day and can attain his routine lifestyle from the next day. Non-invasive nature of the treatment makes it safe and helps in quick recovery as compared to invasive surgery procedures. Non-invasive procedure, safe, and rapid recovery are projected to drive the lithotripsy device market. Several risks are associated with lithotripsy treatment. This treatment is not considered for patients suffering from bleeding disorder and pregnant women. The results are much satisfactory in case of large stones than small stones. Sometimes the procedure results in internal bleeding and may need blood transfusion. It can lead to adverse side effects where kidney may be damaged due to blockage in flow of urine passage caused because of tiny stone particles. Complications such as high blood pressure and above factors restrain the market.

The lithotripsy device market can be segmented based on technology, application, and region. In terms of technology, the market can be segmented into intracorporeal lithotripsy and extracorporeal lithotripsy. Intracorporeal lithotripsy can be sub-segmented, based on instruments used for generation of energy and breaking of stones, into mechanical lithotripsy, electrohydraulic lithotripsy (EHL), laser lithotripsy, and ultrasonic lithotripsy. EHL and laser lithotripsy require direct visualization, which becomes difficult technically. Intracorporeal lithotripsy is carried out with the help of ureterscopy in cases where extracorporeal lithotripsy is not possible due to its position, size, and density. Extracorporeal lithotripsy also termed as extracorporeal shock wave lithotripsy (ESWL) is carried outside the body where high energy shock waves are allowed to pass through the body. The energy generator is used to attain required intensity of shock wave which cleaves the large stone into tiny sand size particles. ESWL has rapidly replaced the surgery options due to its non-invasive nature, outpatient process, and quick recovery.

Based on application, the lithotripsy device market can be segmented into kidney stone, pancreatic stones, bile duct stone (biliary lithotripsy). Lithotripsy seems to be safe and reliable treatment for bile duct stone and pancreatic stone. Rise in prevalence of kidney stone disorders and awareness about lithotripsy technology among urologists has estimated to cover the largest market in this segment.

In terms of region, the lithotripsy device market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. Europe is estimated to be the largest market for lithotripsy devices. Asia Pacific is anticipated to be the fastest growing market due to its new and advance technology development and awareness about these technology among the population and health care sector.

Key players in the lithotripsy device market are Siemens Healthineers, Medtronics, Boston Scientific, DirexGroup, Ince Medical, ELMED Elektronik ve Medikal San. TIC. A.S., Grupo Maxwerk, Haiying Enterprises Group Co. Ltd., and Olympus Corporation.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

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Global Scaffold Technology Market Analysis, Trends and Forecast by 2016 - 2024

Scaffolds are artificial extracellular matrices that support 3D tissue regenerations and accommodate cells. These can be temporary or permanent matrices which provide chemical, mechanical, and biological support for tissue formation. Scaffold technology is employed to perform 3D culture assays that include cell to cell interactions, high throughput screening, cell to matrix interactions, transfections, and cell migration assays. Growing regenerative technology has been attributed to the growth of the scaffold technology market which has led to the development of bio-scaffolds. Scaffolds act as a template for tissue formation, which are subject to biophysical stimuli through a bioreactor, a system which applies chemical and mechanical stimuli to the cells; or are provided with growth factors.

In terms of material, the scaffold technology market can be segmented into bio-inert, bioresorbable, and bioactive. Based on technology, the market can be segmented into nanofiber-based scaffolds, polymeric scaffolds, hydrogels, and micro-patterned surface microplates. In terms of application, the scaffold technology market can be segmented into drug development, tissue culture, cancer treatment, stem cell research, and regenerative technology. End-users in the scaffold technology market include biotechnology and pharmaceutical organizations, research laboratories, hospitals, and diagnostic laboratories. In terms of region, the market can be segmented into North America, Latin America, Asia Pacific, Europe, and Middle East & Africa.

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Scaffold technology provides opportunities to address the challenges associated with tissue culture such as vascularization and enable organ implant regeneration employed in the treatment of damaged and diseased organs or tissues. Increasing number of applications would contribute to the growth of scaffold technology market. In addition, rising accidents leading to organ damage and increase in geriatric population that add to the rising number of people with non-functioning of organs contribute to the growth of the scaffold technology market. In addition, ongoing research on designing matrix-based 3D substrates that enable interaction between implants and host microenvironment for optimal functioning of the implanted cells and drug release is expected to boost the market in terms of revenue during the forecast period. However, the emergence of scaffold-free technology for cell culturing is expected to hamper the scaffold technology market during the forecast period.

Hydrogels based scaffolds are expected to dominate the scaffold technology market due to the continuous progress in their development. However, nanofiber-based scaffolds are expected to record highest growth rate during the forecast period, owing to the growing nanotechnology and their ability to mimic nanoscale properties. Growing investments by biotechnology companies for the development of products related to scaffold technology is expected to contribute to the growth of the scaffold technology market.

North America is expected to dominate the scaffold technology market. Growth of the market in the region can be attributed to well-developed infrastructure in the region, ongoing research, and the presence of major market players in the region. However, the scaffold technology market in Asia Pacific is expected to record the highest growth rate during the forecast period, owing to the increasing government focus on boosting research and development in the pharmaceutical industry and the improving health care infrastructure in the region.

Leading players in the scaffold technology market include 3D Biomatrix, 3D Biotek LLC, Acelity (LifeCell Corporation), Avacta Life Sciences Limited, Becton, Dickinson and Company, Medtronic (Covidien plc), Merck KGaA (Sigma-Aldrich Co. LLC), Molecular Matrix, Inc., Molecular Partners, Nanofiber Solutions, NuVasive, Inc., Pelo Biotech GmbH, ReproCELL Europe Ltd. (Reinnervate), Thermo Fisher Scientific, Inc., Vericel Corporation, and Xanofi. The leading players in the market have been focusing on diversifying their product portfolios and expanding their distribution networks to strengthen their market position.

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Friday 26 May 2017

Global Surgical Stapling Devices Market Share by Industry Research 2016 - 2024

Global Surgical Stapling Devices Market: Overview

Surgical stapling devices were developed in response to rising concerns regarding the healing of traditional sutures. Compared to modern surgical staplers, sutures are more prone to separation and leaks. Additionally, surgical stapling devices offer a number of advantages over sutures such as accuracy, speed, and evenness of wound closure.

According to the US Food and Drug Administration (FDA), surgical staplers have been on the market for years now and these complex mechanical medical devices have been maturing in their technology. Employed in gynecologic, gastrointestinal, thoracic, and several other surgeries, surgical stapling devices are used to cut through tissues and organs, to remove part of an organ, and to develop connections between structures.

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Two major types of surgical stapling devices are available in the market: manual and powered. These devices can be either reusable or disposable. Either way, both types are loaded with disposable cartridges. Geographically, the global surgical stapling devices market covers four main segments: Asia Pacific, North America, Europe, and Rest of the World.

This report offers readers a comprehensive and objective assessment of the global surgical stapling devices market and serves as an ideal blueprint for those looking to expand or enter into a business in this avenue. Supported with accurate facts and figures pertaining to the historical, current, and future performance of the surgical stapling devices market, the report offers actionable insights into where the market is headed and the key factors driving and hampering its growth. The most prominent players competing in the space are also highlighted and reviewed based on recent developments, product portfolio, business strategies, and financial standing.

Global Surgical Stapling Devices Market: Key Trends and Opportunities

The global surgical stapling devices market is single-handedly propelled by the rise in the number of surgeries performed around the world. The demographic trend of increasing geriatric population, growing prevalence of chronic diseases, presence of favorable reimbursement scenarios in developed and developing countries, and advancing medical tourism industry have contributed toward the increase in cardiovascular, neurological, and orthopedic surgeries, among others. This growth in surgical procedures has boosted the demand for surgical stapling devices significantly. Advent of new technologies, highly developed health care infrastructure in developed countries, rising demand for powered surgical instruments and accessories in emerging economies, and growing accessibility to health care facilities in developing countries are the other factors contributing to the expansion of this market.

Global Surgical Stapling Devices Market: Region-wise Outlook

Europe and North America are the dominant regional markets for surgical stapling devices and are likely to retain their lead during the forecast period. These regions are primarily driven by the early acceptance of advanced product innovations and technically advanced equipment. Asia Pacific is a much smaller market compared to the aforementioned developed markets; however, the potential for growth in the region is exceptional.

The RoW segment of the global market also holds immense scope for growth. The patient pool in Asia Pacific and RoW is high, thus translating into an increased number of surgical procedures and soaring demand for surgical stapling devices. Rising awareness about the availability and use of advanced surgical equipment and increasing health care expenditure in several developing countries are also likely to boost the surgical stapling devices market in Asia Pacific and RoW.

Conmed Corporation, Alcon Laboratories Inc., KLS Martin Group, Zimmer Holdings Inc., Stryker Corporation, Ethicon Inc., Smith & Nephew PLC, Medtronic Inc., and CareFusion Corporation are some of the leading players operating in the global surgical stapling devices market.

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Global Combined Angiography Market Analysis, Trends and Forecast by 2016 - 2024

Angiography is an X-ray imaging technique in which, contrasting agents are injected into the blood stream to visualize the blood vessels and help understand the abnormalities of blood vessels such as aneurysms and atherosclerosis. It is commonly used for diagnosing the heart diseases such as Coronary artery diseases. According to WHO, in 2012, 17.2 million people have died from cardiovascular diseases globally. Among them, 42.2% of the population were victims of the coronary artery disease. Computed Tomography (CT), angiography, and Magnetic Resonance Imaging (MRI) angiography are new angiography techniques that are used to diagnose abnormalities in blood vessels. These procedures are heal comparatively faster than conventional X-ray angiography technique (digital subtraction angiography). However, in this procedure, only abnormalities in blood vessels are diagnosed whereas conventional angiography helps in diagnosing abnormalities and treating blocked arteries.

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Hence, in recent years angiographic imaging system vendors have developed combined angiography device systems, which have both DSA and CT scan to treat and diagnose the blood vessel abnormalities. These devices are present in two different operating rooms to diagnose and treat the blood vessel diseases due to which, most of the time is often lost in transferring the patients from the CT room (Diagnosis) to angio room (Treatment). Hence, combined angiography system plays an important role in treating and diagnosing the patient in same operating room and reduces space for the equipment.

These systems have a new 3D-application which links the angiography systems with CT images previously taken during the interventional process. Hence, the systems provide exceptional imaging qualities and makes it easier for surgeons to conduct surgeries. Few companies have developed mobile platforms to enable the multidisciplinary teams perform the procedures comfortably without any obligatory access to patients. In addition to these, systems will provide precision dosing, which expose the patient to less radiation as compared with the conventional system.

These systems have multiple-utility application areas, rising incidence of cardiac diseases, adaptation to new technologies and increasing awareness about the disease are the major factors driving the growth of combined angiography market. Complex regulatory process and the high cost of these systems are limiting factors for the combined angiography system market in the forecast period.

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Global Bone Staple Systems Market Analysis, Trends and Forecast by 2016 - 2024

A bone staple is conceptually a single fixation device made up of 2 or more points of entry into bone that are joined to each other. By design, it is fabricated as a fixed metal device of single construction and variable thickness made up of 2 or more legs of varying length with sharp tips joined by a bridge of varying width that is driven directly into bone typically with a hammering motion. The bone staple essentially represents simplicity in design and use. In the standard application, the bone staple is simply pounded into the bone to help stabilize a fracture or osteotomy to promote bone healing. Bone staples can be used as adjuncts to other forms of fixation or as single or multiple bone staples at one site.

The increasing evidence of the accident, increasing geriatric population, rising cases of osteoporosis will drive the market of bone staple system. The large variety of bone staple systems are available in the market. These products are used for the fixation of broken bone. The system comprises pins like a stapler, the pins are fixed or drilled in the body by surgery for certain period or permanently depends on the medical condition.

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The basic use of a bone staple is in neutralization. Bone staples are also utilized in terms of application to support loose fragments to help prevent their movement or migration. By placing a pre-insertion compression force at the fracture or osteotomy surfaces; stabilizing opposite a side of compression as a tension band; or inserting the staple with divergent legs, compression forces can be achieved across the fracture or osteotomy surfaces even in the absence of mechanical or metallurgical mechanisms.

The bone staple system market is segmented as product type, End User, and Geography. The product type market is further segmented into four types such as, table fixation staples, osteotomy fixation staples, regular fixation staples and Krackow HTO staples. The fixation staples are used for a variety of applications such as knee ligament repair, ankle fracture, triple arthrodesis, epiphysial growth arrest, arthrodesis of the ankle and wrist and others. The osteotomy fixation staples are highly used in high tibial osteotomies to recover valgus deformities. For fixing soft tissue to bone including anterior cruciate reconstruction regular fixation staples are widely used. They are also convenient for fragment fixation, ligament, and tendon fixation and in controlling bone growth. The Krackow HTO staples are most useful in high osteotomies.

By End User, the bone staple system market is segmented in hospitals, orthopedic centers, ambulatory surgical centers and clinics. Hospitals segment hold largest market share in overall bone staple market was owing to increasing number of emergency patients and patients suffering from orthopedic disorders. The orthopedic centers comprise the second rank after hospitals as an increasing number of orthopedic centers in economically growing countries.

By geographically the bone staple system market is segmented in North America, Europe, Asia-Pacific, Latin America, Middle East & Africa. The North America is the most lucrative market for bone staple system as the availability of facilities and products in the region is more. The awareness among the population of North America and Europe about the product is more hence the demand is more in the region. The increasing medical tourism in countries like India, China, Japan will also drive the bone staple system market in Asia Pacific.

The increasing evidence of osteoporosis after post menopause in women's is the major driving factor of bone staple system market. The increasing competition in the market players for bone staple market as the acceptability of products are more due to increasing knowledge of product among patients. Some of the major companies in bone staple system market are Stryker, Arthrex, Smith and nephew, Instratek, Nextremity Solutions, Inc., Neosteo, Synthes, Wright Medical Technology and Zimmer Holdings.

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Gouty Arthritis Market - Global Industry Volume and Region Analysis - 2024

Affecting approximately 1 in 40 adults, Gouty arthritis is characterized by severe swelling and attacks of pain, tenderness, redness, warmth and swelling in the joints that result from abnormal metabolism of uric acid in the tissues and blood. Usually, the joint at the base of the big toe gets affected due to redness, stiffness, swelling and burning pain. High blood pressure, high cholesterol, diabetes and heart disease may increase of gouty arthritis. Affecting mostly men between the ages of 30 to 60 years, Gouty arthritis is primarily caused by the accumulation of too much uric acid in the joints that causes nodules under the skin, known as tophi. Increased levels of uric acid in the blood results from chronic kidney disease, obesity and certain medications (diuretics). One is more likely to have gouty arthritis if there is a family history about it while obese people are at a higher risk for gout. Sometimes, consumption of high-protein food, sudden changes in diet and weight gain or loss may also produce excessive amount of uric acid. One of the most painful forms of arthritis, Gouty arthritis is typically more common in men than in women and future damage to joints can be avoided by treatment.

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Based on geography, the gouty arthritis market can be segmented into four major regions: North America, Europe, Asia Pacific and Rest of the World (RoW). Out of these regions, North America holds a leading position in the gouty arthritis market followed by Europe. The prime factors which are driving the growth of the market in these regions are increasing awareness amongst the patient population, consumption of high-protein food and certain sedentary habits such as smoking tobacco and drinking. Furthermore, increasing disposable income of the population is also propelling the growth of gouty arthritis market. Asia Pacific is the most promising region for the growth of gouty arthritis market as it is one of the emerging economies. The factors which would accentuate the growth of the market in Asia Pacific are increasing prevalence of obesity and certain genetic disorders, and development of therapeutic treatment as well as testing tools for the treatment of gouty arthritis. Moreover, huge population base in developing countries such as China, India and Brazil would also fuel the growth of gouty arthritis market in the coming years.

Gouty Arthritis Market Key Players

Some of the top players operating in the development of gouty arthritis therapeutics market are AstraZeneca PLC, Novartis AG, Polaris Group, BioCryst Pharmaceuticals, Inc., Teijin Pharma Limited, Nippon Chemiphar Co., Ltd., JW Pharmaceutical Corporation, Addex Therapeutics, LG Life Sciences, Ltd. and others.

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Global Uterine Fibroid Diagnostics and Therapeutics Market Share by Industry Research 2016 - 2024

Uterine fibroid is a type of tumor that arises from the smooth muscle tissues of uterus. Common non-cancerous growths that develop in the muscular wall of the uterus, they are also known as leiomyoma (benign tumor), fibroleiomyoma, fibromyoma and myoma. They vary in size from tiny to larger than a cantaloupe. Sometimes, they led the uterus to grow to the size of a five-month pregnancy. Fibroids presence usually is multiple is number and if its number is uncountable, it is referred to as uterine leiomyomatosis. Fibroids are amongst the most common form of benign tumors and usually affect the females during the middle of reproductive age and later reproductive age. The malignant form of fibroid, known as leiomyosarcoma, is very uncommon.

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Uterine fibroids are usually asymptomatic, however once they start growing, they create various problems such as painful and heavy menstruation, affecting urine urgency and frequency, and painful sexual intercourse. It sometimes, may also interfere with pregnancy and dramatically increase in size during pregnancy. It is thought to be because of increase in levels of estrogen during pregnancy. It does not affect the women post menopause as the level of estrogen that circulates in the blood, reduces drastically. However, women who are taking estrogen supplement in hormone replacement therapy are expected to experience the symptoms disease.

Uterine fibroids are of various types namely subserosal fibroids, intramural fibroids and submucosal fibroids. Subserosal fibroids develop under the uterus outside covering and expand outward through uterine wall and result in knobby appearance of the uterus. Intramural fibroids develop into the lining of the uterus and hence, expand inward resulting in increase in the size of uterus. Amongst all, it is the most common uterine fibroids. Submucosal fibroids develop under the uterus linings and it causes various medical conditions such as heavy bleeding and prolonged menstruation. It is rarest of all uterus fibroids.

Uterine fibroids can be diagnosed using various imaging modalities such as medical resonance imaging (MRI) scanners, computed tomography (CT) scanners and ultrasound devices. Amongst all, ultrasound devices are used extensively for diagnosing uterine fibroids owing to its efficiency and popularity for gynecological purpose. Also, it does not produce any harmful rays that may harm the fetus (if women suffering from uterine fibroids is pregnant), increasing its preference among radiologist. Other diagnosing procedures include hysterosonography, hysterosalpingography and hysteroscopy.

Various treatment procedures have been adopted by physicians to cure the disease that include nonsurgical uterine fibroid embolization, magnetic resonance guided focused ultrasound, myolysis, endometrial ablation and resection of submucosal fibroids, hysterectomy and myomectomy surgery. Among all the aforementioned treatment procedures, nonsurgical uterine fibroid embolization is the most extensive used method of treatment. Various medications are also advised to the patients suffering from uterine fibroids that include gonadotropin-releasing hormone agonists, progestin-releasing intrauterin, progestins or oral contraceptives and nonsteroidal anti-inflammatory drugs.

The market for uterine fibroid diagnostics and therapeutics is expected to grow at a significant CAGR during 2014 to 2020. This growth is primarily driven by increasing number of women of reproductive age (WRA) across the globe. According to the Centers for Disease Control and Prevention (CDC), approximately 60 million WRA were reported in 2012 and this number is expected to rise with increasing number of women globally. According to the World Data Book, total population of women was around 3,439.4 million in 2011 and this number is expected to grow due to improving education systems mainly in developing countries such as India and China. Other factors that are also supporting the growth of uterine fibroid diagnostics and therapeutics market are rising prevalence of uterine fibroids and change in lifestyle mainly dietary pattern. Low intake of fruits and green vegetables increases the risk for developing uterine fibroids.

Uterine Fibroid Diagnostics and Therapeutics Market Key Players

The major players operating in the uterine fibroid diagnostics and therapeutics market include Roche Ltd, Abbott Laboratories, Becton, Dickinson and Company and Siemens Healthcare among other significant players.

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Global Hypercholesterolemia Market By Analysis of Major Industry Segments 2015 - 2023

Increased level of total cholesterol and LDL (bad) cholesterol in the blood leads to hypercholesterolemia. The normal biological range of total blood cholesterol is 140-200 mg/dL. Hypercholesterolemia leads to cardiovascular diseases such as atherosclerosis, stroke etc. Human blood cholesterol mainly consists of High-density lipoprotein (HDL) cholesterol, Low-density lipoprotein (LDL) cholesterol, Very low-density lipoprotein (VLDL) cholesterol. HDL cholesterol is termed as good cholesterol for the body. High level of HDL cholesterol reduces the risk for heart diseases and HDL naturally removes cholesterol from cells by reverse cholesterol transport to the liver. On the other, hand LDL adds to plaque, a hard and dense deposit that blocks the arteries and make the artery wallless flexible. This type of medical condition is termed as atherosclerosis. Clot forms and blocks the narrowed arteries leads to heart attack, stroke and peripheral artery diseases.

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Hypercholesterolemia usually result from the grouping of genetic and environmental risk factors. Genetic disorder leads to heterozygous familial hypercholesterolemia. It happens due to the existence of the mutated copy of the LDLR gene (LDL receptor gene). Individuals with the homozygous gene, containing dual copies of the gene mostly suffer from severe cardiovascular diseases in their childhood and people with the heterozygous gene that is with a solitary copy of the gene suffer from cardiac ailment in their 30s or 40s.

Hypercholesterolemia due to lifestyle selections includes unhealthy eating habits, lack of exercise, and intake of tobacco smoking strongly hampers the quantity of cholesterol in the blood. However, there are few secondary reasons as well such as diabetes mellitus (Type 2), alcohol intake, obesity, monoclonal gammopathy, dialysis and others.

The hypercholesterolemia treatment market is increasing at a substantial rate due to technologically advanced diagnosis, government initiatives, improved reimbursement scenario lifestyle changes, rising awareness about different cardiovascular diseases. Treatment for hypercholesterolemia mainly includes intake of statins and opting for a better lifestyle. Factors such as high cost in the diagnosis, lack of awareness and lack of knowledgeable experts for proper diagnosis of the disease are restricting the global market for hypercholesterolemia treatment.

North America rules the global market for hypercholesterolemia treatment reason beingincreased incidences of heart diseases and related disorders in the region. Asia, followed by Europe, predicted to witness a high growth rate in coming years in the hypercholesterolemia market. Developing countries like China and India are also growing fast in these markets by the presence of a large patient pool and growing government initiatives. Hypercholesterolemia Market can be segmented as drug class and geography. Drug class can categorize hypercholesterolemia market as statins, niacin, bile-acid resins, fibric acid derivatives, cholesterol absorption inhibitors.

Some of the key players in this Hypercholesterolemia market AbbVie, Inc., AstraZeneca Plc., Amgen, Inc., Eli Lilly and Company, Merck & Co., Novartis AG and Pfizer, Tekmira Pharmaceuticals Corporation.

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Bacterial Disease Diagnostic Market - Global Industry Analysis and Forecast 2015 - 2023

Bacteria are of various types some of them are infectious whereas, majority of them are beneficial for the body. Any bacteria that cause an infectious disease are called pathogens. Diagnosis of causative organism of a bacterial disease has always been difficult, since infections show similar symptoms like fever and lethargy. Routine clinical diagnosis have high error rate, administering the wrong antibiotics can sometimes increase infection and can even result in death. The oldest method for diagnosis has been culturing of bacteria, these cultures allow only specific species to grow in the medium, however this method is very time consuming and can seldom be done on time to successfully diagnose and treat the patient. Newer techniques like rapid culture methods with ionized mass spectrometry are currently in use for diagnosing some rare bacteria.

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Currently, PCR (Polymerase Chain Reaction) sequencer is the most favored and well know method. The PCR can amplify bacterial DNA a thousand times if necessary, any routine diagnosis requires only a min of 10 – 80 bacteria, which means PCR has a very high sensitivity. This factor is exploited for countless diagnostic processes. PCR also doesn’t require purification of the bacterial sample compared to older methods as it has specific sequences to identify bacterial DNA. Versatility of PCR has proven to be a big advantage, diagnosis of many dangerous diseases like tuberculosis, pneumonia etc are done with the intention to specify whether the strain is drug resistant. This greatly increases the success rate of treatment. The shortcomings of PCR are also eminent; PCR is susceptible to false positive report in presence of any contamination, it is also not useful in calculating the success of a treatment, as PCR recognizes dead and living cells as the same. Technical expertise is a major requirement in PCR handling. PCR techniques also require a number of biochemical reagents that are quite expensive. Development has been made to create more specific and customized versions of PCR machines with greater accuracy and low false positive rates. These include; PCR ribotyping techniques which are much faster and highly specific to certain strains; multiplex PCR that can detect multiple pathogens in a single go and nested PCR a modified error negating version of PCR. Such modified versions are currently available in laboratories and are offered as a diagnostic service and are seldom used as a large-scale diagnostic tool. However, with the entry of novel ‘portable PCR’ there is a scope for diagnostic evolution in future.

On the other hand, scientists throughout the world are developing ideas in Electrophoresis methods and tests for biological proteins that are produced in the body in reaction to an infection. In newborns such tests are done to investigate the diseases that have late onset period. With increasing population and globalization, the chance of infection remains high, diseases too have gone global. In addition, diagnosing a disease before it becomes an epidemic is very critical. Thus, PCR and electrophoresis machines helps in early and fast diagnosis of these diseases that leads to an increase in the demand for PCR and electrophoresis machines. However, lack of skilled professionals/technicians and high cost of these devices restricts the overall growth of bacterial disease diagnostics market.

Some of the companies that produce PCR machines are Techne, GeneriBiotech, Roche diagnostics and ZyGEM to name a few. The sales of these devices are currently highest in the developed nations of the North Americas and Europe whereas, Asia-Pacific region shows the highest growth followed by South America and Africa.

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