Thursday 7 August 2014

Prokaryotic Expression Systems Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020

Transparency Market Research Reports incorporated a definite business overview and investigation inclines on “Prokaryotic Expression Systems Market”. This report likewise incorporates more illumination about fundamental review of the business including definitions, requisitions and worldwide business sector industry structure. Expression systems are used for the production of large number of biological products such as proteins, enzymes, amino acids, biopolymers from recombinant DNA molecules. The process involves introduction of a foreign DNA into the host cell. The first step involved in various biomolecule production using expression systems is identifying and isolating the DNA to be introduced into the host. This is followed by vector identification and construction of recombinant vector. An expression vector or plasmid which is responsible for protein expression in cell possess various components such as promoter, translation initiation sequence, start codon, termination codon and transcription termination sequence. Among the two general expression systems such as prokaryotic and eukaryotic systems, prokaryotic expression systems produce large quantities of protein quickly and economically using bacterial host organisms such Escherichia coli, Pseudomonas. alcaligenes, Corynebacterium glutamicum, and Bacillus subtilis. Advances in genetic engineering, ability to clone and express a gene in the heterologus host have made possible the capability to produce any protein as a diagnostics and therapeutic agent. A large number of expression vectors are available commercially or in research laboratories, though only limited numbers of vectors are suitable for industrial use. Certain factors affecting prokaryotic expression system include codon bias, protein folding, protein phosphorylation and glycosylation and promoter strength.
The global prokaryotic expression systems market has been segmented into host types, end users, products, applications and geography. Host types have been further segmented into E. coli systems, C. glutamicum, P. alcaligenes, B. subtilis and archaea. End users for prokaryotic expression systems include contract research organizations, academic research, pharmaceutical and biotechnology companies and others. Applications for the prokaryotic expression systems include industrial proteins, research and therapeutic proteins. Products obtained from prokaryotic expression systems include enzymes, antibiotics, amino acids, pigments, biopolymers, lipases and ascorbic acid. Geographically, the prokaryotic expression systems market can be categorized into four major regions namely North America, Europe, Asia-Pacific and Rest of the World. Growth in biologics and proteomics and the associated increase in research activities are expected to drive the growth of the global prokaryotic expression systems market. Emerging economies of Asia Pacific, Latin America, and the Middle East countries present significant opportunities for the growth of this market.
E. coli is one of the most popular hosts for artificial gene expression. Production of proteins with the help of E. coli is the simplest, cheapest and quickest method. There is a vast amount of knowledge about the genetics, genomic sequence and physiology of E. coli greatly facilitating gene cloning and production thus making it a popular and most widely employed host. Furthermore, ability to express heterologus proteins in a huge quantity i.e. higher volumetric productivity along with high growth rates also makes E. coli the most suitable host. Corynebacterium is a non pathogenic gram positive bacteria are used for commercial production of amino acids such as glutamate and lysine as well as components of animal feed and pharmaceutical products. C. glutamicum species has been used for expression of functionally active human epidermal growth factor. P. fluorescens is used for development of vaccines and bio therapeutics.
However certain limitations with the use of prokaryotic expression systems include inappropriate mechanism of post translational modifications. Also, E coli possess toxic cell wall pyrogens and thus require extensive testing before use of products. Moreover, prokaryotic proteins synthesized in bacteria sometimes are unstable or lack biological activity. Stabilization and formulation of proteins for their use in industrial and therapeutic applications with the help of biological catalysts is further expected to pose a challenge to the success of prokaryotic expression systems.
Some of the key players contributing to the global prokaryotic expression systems market include Agilent Technologies, Inc., Bio-Rad Technologies, Inc., Merck Millipore, Promega Corporation, Qiagen, Sigma Aldrich Corporation and Thermo Fischer Scientific, Inc. amongst various others.
This research report analyzes this market depending on its market segments, major geographies, and current market trends. Geographies analyzed under this research report include
  • North America
  • Asia Pacific
  • Europe
  • Rest of the World
This report provides comprehensive analysis of
  • Market growth drivers
  • Factors limiting market growth
  • Current market trends
  • Market structure
  • Market projections for upcoming years
This report is a complete study of current trends in the market, industry growth drivers, and restraints. It provides market projections for the coming years. It includes analysis of recent developments in technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also includes a review of micro and macro factors essential for the existing market players and new entrants along with detailed value chain analysis.
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Machine To Machine Market: New Industry Research Report is Now Available for Pre-Order at Transparency Market Research

Machine To Machine Market

Machine to Machine also known as M2M, is a cumulating set of technologies which combines both wireless and wired network systems for communicating with other devices. The basic components of M2M systems are a sensory device which grabs signals and transmits them further to a network which could be both wireless as well as wired; an application software to process such data and finally into a relevant information. Certain major machine to machine technologies which are currently in vogue are 2G and 3G technologies, Wireless Fidelity (WiFi), Ethernet, ZigBee etc.


Machine to machine technology has vast application in the fields of vehicular infotainment, medical and healthcare industry, GPS or vehicular tracking, digital signature and authentication etc. Some of the major drivers of this market are the current relevance of high tech applications like 3G and 4G technology and usage of various technological applications. Whereas the need to follow regulations created by authorities and increasing scope of cloud computing is also driving this market.

There are also certain holdbacks of this market. They are - requirement of huge sums of money for initial investment, low level of technical awareness in underdeveloped nations and certain inoperability constraints. However with growing implementation of this technology, it is expected that these restraints can be overcome. Increasing usage of computers and other IT applications in almost every industry can be viewed as a potential opportunity for the machine to machine market.

Owing to high technological advancement and technical awareness in developed nations, countries like the U.S. and U.K. are the largest market for this technology. Europe also follows a similar trend. Emerging nations of Asia Pacific also hold tremendous growth potential in the machine to machine market.

Some of the major players of this market are Axeda Corporation, Atmel Group, Cisco Systems, Freescale Semiconductor Inc, Infeneon Technologies AG, Cypress Semiconductor Corporation, NEC Corporation, Novatel Wireless, Numerex Corp, NTT DOCOMO Inc etc.

This research report analyzes this market depending on its market segments, major geographies, and current market trends. Geographies analyzed under this research report include
  • North America
  • Asia Pacific
  • Europe
  • Rest of the World
This report provides comprehensive analysis of
  • Market growth drivers
  • Factors limiting market growth
  • Current market trends
  • Market structure
  • Market projections for upcoming years
This market research report analyzes important market segments, and major geographies. This report is a complete study of current trends in the market, industry growth drivers, and restraints. It provides market projections for the coming years. It includes analysis of recent developments in technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also includes a review of micro and macro factors essential for the existing market players and new entrants along with detailed value chain analysis.


About us

Transparency Market Research (TMR) is a market intelligence company providing global business research reports and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision-makers.

TMR’s experienced team of analysts, researchers, and consultants use proprietary data sources along with various tools and techniques to gather and analyze information. Our business offerings represent the latest and the most reliable information which is indispensable for businesses to sustain their competitive edge.




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